University of Wisconsin–Madison

Radiopharmaceutical Production Facility

Start a Radiopharmacuetical Request

A facility designed for the production of radiopharmaceuticals for preclinical and clinical research


To develop and manufacture high-quality standard and novel radiopharmaceuticals, in order to support and advance preclinical and clinical translational PET molecular imaging and radiotherapy research and clinical trial services. Our goal is to provide this in an environment emphasizing safety and reliability, insuring a high level of quality in compliance with current federal regulations and guidelines.

About the Facility

The University of Wisconsin Radiopharmaceutical Production Facility (RPF) is situated within the Wisconsin Institutes of Medical Research, located at the University of Wisconsin School of Medicine and Public Health. It houses a new manufacturing area designed for the production of cGMP radiopharmaceuticals. This area is equipped with multiple hot cells and synthesis modules and includes multiple quality control instruments to accommodate segregation of clinical and preclinical production activities. Additionally, a dispensing area designed in compliance with USP <797> has the capability to compound and distribute radiopharmaceuticals.

Services and Interests

  • PET radiopharmaceutical production and imaging to support human clinical studies
  • Production of literature PET (small molecule and biologics) and radiotherapy agents
  • Preclinical and clinical development of novel PET imaging and therapeutic agents
  • Production of 18F, 11C, 13N-ammonia, and 68Ga PET radiopharmaceuticals
  • On-site availability of 89Zr and 64Cu radioisotopes for research
  • Request Radiopharmaceutical Assessment and Development

Nuclear Pharmacy

  • Shielded fume hoods for custom compounding
  • Laminar Flow hoods
  • Designed for USP <797> compliance
  • Dispensing area for distribution


  • Multiple Bq and Sv Production Hot Cells
  • Custom-Made Hot Cells
  • Multiple Synthesis Modules
  • Laminar Flow Hood
  • 68Ga Generator

Quality Control

  • Gas Chromatographs
  • HPLC Units
  • Multi-Channel Analyzers
  • Dose Calibrators
  • TLC Scanner
  • Biological Safety Cabinets
  • Incubators

Associated Facilities

  • PET Imaging Center
  • UW Medical Physics Cyclotronexternal link
  • UW Carbone Cancer Center Small Animal Imaging Facilityexternal link