University of Wisconsin–Madison

Using MRI to Visualize Regional Therapy Response in Patients with Idiopathic Pulmonary Fibrosis

This project was led by: Sean B Fain PhD

This project was funded by: NIH

The term of this project was: October 2015 to October 2018

The number of subjects scanned during this project was: 74

This is a two-center, NIH-sponsored study to evaluate MRI imaging for adults with Idiopathic Pulmonary Fibrosis (IPF) and healthy normal adults. The study involves obtaining pulmonary function tests before and after MRI imaging sessions. The MRI sessions include the inhalation of Xenon. One of the goals of this study is to establish an MRI test that will provide a comprehensive, quantitative assessment of the structure and function of the lungs that can be used to monitor progression and responses to therapy in patients with IPF. The ultimate scientific objective is to develop a diagnostic test that might predict patient outcomes.