University of Wisconsin–Madison

FH Swine Pilot Study

October 2011 to April 2011

Our collaborators in the UW Department of Animal Sciences have a unique population of swine with familial hypercholesterolemia. As such, they develop early atherosclerosis. The goal of our project is to develop MRI-based biomarkers of atherosclerosis with the hope that we can detect disease burden in these swine before conventional methods of detection. 3D angiography will be very beneficial to the study, as it will allow us to confirm the presence of plaques and therefore assess whether or not our MRI-derived biomarkers can detect the atherosclerotic lesions seen with angiography.

This project led by: Andrew Wentland, PhD