University of Wisconsin–Madison

The Study of Brain Aging in Vietnam War Veterans (DOD-ADNI)

March 2013 to October 2014

The purpose of this research study is to examine the possible connections between Post Traumatic Stress Disorder (PTSD) and/or Traumatic Brain Injury (TBI) and the signs and symptoms of Alzheimer’s disease (AD) in Veterans as they age. Three groups will be scanned; one group with PTSD, one group with TBI, and one control group. MRI scans will be conducted at both a screening visit and an annual visit for each participant to assess suitability for study participation, and to also assess whether or not there is increased brain atrophy in hippocampus, entorhinal cortex, and parietal/temporal cortices, and increased longitudinal rates of brain atrophy in hippocampus, entorhinal cortex, and parietal/temporal cortices in participants with TBI/PTSD as compared to the study controls.

This project led by: Sterling Johnson, PhD