University of Wisconsin–Madison

The Clinical, Biomechanical, and Tissue Modifying Effects of a Single Platelet-Rich Plasma Injection for the Treatment of Chronic Patellar Tendinopathy: A Randomized Controlled Trial

January 2014 to December 2015

. It is hypothesized that acoustoelastography is able to measure these mechanical changes to differentiate disease-specific tissue states of tendons, ligaments, or patellar tendon. The AE method involves only a post processing analysis of grey scale images acquired during a conventional ultrasound exam. Therefore, information obtained from AE analysis is in addition to the grey scale images obtained during the conventional ultrasound exam. However, AE analysis does not require additional scanning time for the patient. Conventional ultrasound is well known for its biosafety profile of non-ionizing radiation, accessibility, and cost saving. AE, similar to how Doppler can add information to conventional grey scale images in detecting blood flow, adds mechanical information to the conventional ultrasound exam.
Correlating US and acoustoelastography imaging assessments with validated clinical outcomes will provide a powerful tool for future outcomes analyses using a non-invasive imaging modality to monitor tissue healing both morphologically as well as biomechanically, and may even be used to evaluate injury risk.

This project led by: John Wilson, MD