University of Wisconsin–Madison

Prediction of Liver Segment Hypertrophy After Portal Vein Embolization Using 4D Flow MRI

August 2015 to February 2016

Portal vein embolization is a technique to make healthy liver parts grow in order to be able to resect a part of the liver affected by a tumor. This is achieved by blocking blood vessels to the tumorous part of the liver, so that more blood flows to the healthy part of the liver and it grows larger.
In this study, we will use 4D flow MRI to measure the flow of blood to the healthy part of the liver to determine if blood flow correlates with the growth rate of the liver. In doing this, we can see if we can predict the growth rate of the healthy parts of the liver based on changes in blood flow. This is desirable in order to schedule resection of liver segments containing tumor as early as possible. If it can be determined that the healthy part of the liver is growing large rapidly, this may allow the tumerous part of the liver to be removed sooner, before maximal growth of the healthy part of the liver has been achieved.

This project led by: Tilman Schubert MD