University of Wisconsin–Madison

Non-invasive Quantification of Liver Iron with MRI

This project was led by: Diego Hernando PhD

This project was funded by: Wisconsin Alumni Research Foundation

The term of this project was: October 2011 to December 2016

The number of subjects scanned during this project was: 100

The purpose of this study is to see if new Magnetic Resonance Imaging (MRI) methods can measure the amount of iron in the liver. Standard methods used to quantify iron levels are expensive, invasive, and/or inaccurate. There is one MRI technique that is approved by the U.S. Food and Drug Administration (FDA) for measuring liver iron, called FerriScan. This study is testing an investigational MRI technique that could potentially be performed faster and at a lower cost. The MRI scans will include both the FerriScan technique and an investigational scan technique. Because the heart can be seen in an MRI of the liver, we will also test this MRI technique for its ability to measure iron in the heart.