Motion Compensation PC HYPR VIPR for MR Angiography

The purpose of this research is to investigate a novel Magnetic Resonance Angiography approach, called PC HYPR VIPR for its role in improving the noninvasive diagnosis of vascular disease from flow-encoded MRI data. This approach was developed at the University of Wisconsin, Madison and would serve as a single robust, easily prescribed scan that would provide detailed anatomical and functional information of both renal arteries and/or other vascular territories. Functional measurements such as velocity and flow waveforms can be directly measured and additional hemodynamic parameters, most importantly pressure gradients, can be directly derived to assist in the detection of hemodynamically significant lesions. The approach offers several advantages over existing non-invasive diagnostic methods, including providing large coverage, very high temporal (the frequency at which images are recorded) and spatial resolution (the clarity and detail of images), anatomical and functional information, easy prescription, and direct derivation of other hemodynamically relevant parameters such as pressure gradients, with no need for contrast agents.