University of Wisconsin–Madison

Magnetic Resonance Imaging of Cerebral Vascular Structure and Blood Flow in Metabolic Syndrome

November 2012 to December 2013

The central hypothesis of this work is that patients with Metabolic Syndrome exhibit markedly blunted cerebral vasodilation, due to structural remodeling and loss of vasodilating prostaglandins. This study investigates regional and global cerebral blood flow changes with MRI measurements in response to exercise dilation, hypoxia or hypercapnia in normal subjects and in patients with Metabolic Syndrome.

This project led by: Bill Schrage, PhD