University of Wisconsin–Madison

Magnetic Resonance Imaging of Cerebral Vascular Structure and Blood Flow in Metabolic Syndrome

This project was led by: Bill Schrage PhD

This project was funded by: American Diabetes Association

The term of this project was: November 2012 to December 2013

The number of subjects scanned during this project was: 60

The central hypothesis of this work is that patients with Metabolic Syndrome exhibit markedly blunted cerebral vasodilation, due to structural remodeling and loss of vasodilating prostaglandins. This study investigates regional and global cerebral blood flow changes with MRI measurements in response to exercise dilation, hypoxia or hypercapnia in normal subjects and in patients with Metabolic Syndrome.