University of Wisconsin–Madison

Bone Bruises: MR Characteristics in the Pig Knee

October 2005 to September 2006

The purpose of the study is to determine the MR imaging characteristics using T1, T2 with fat saturation, and STIR imaging to evaluate marrow signal characteristics following trauma and to document the time interval in which edema can be seen using MRI following trauma. Anesthetized pigs will receive a bone bruise to the knee by an orthopedic surgeon. Pigs will be imaged immediately following trauma, and 4, 12, and 24 hours post trauma to identify the time onset of bone marrow edema following trauma.

MR Protocol: The pigs will be imaged using axial, coronal, and sagittal T1 spin echo, fat suppressed T2 FSE, and fat suppressed IR sequences.

This project led by: Donna G Blankenbaker, MD